Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003252 | 0.81 | RAB9A (0.53) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL18985306 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP2D6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19003345 | 0.77 | MEN1 (0.47) | CYP1A2ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL23591991 | 0.73 | TGM2 (0.60) | CYP1A2CYP2D6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19003348 | 0.73 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL19003351 | 0.70 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL19003350 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL19003261 | 0.69 | MMP1 (0.59) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19003255 | 0.69 | EGFR (0.47) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL19003354 | 0.69 | MMP1 (0.62) | ALDH1A1LMNASMN1; SMN2HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |