Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15450908 | 0.89 | HRH3 (0.57) | ALDH1A1HTTKDRTBK1HRH3 | |
| SCHEMBL18986049 | 0.83 | GABRP (0.53) | ALDH1A1KDM4EKDRTBK1TSHR | |
| SCHEMBL19004116 | 0.82 | TBK1 (0.61) | TBK1IKBKE | |
| SCHEMBL13319011 | 0.81 | L3MBTL1 (0.53) | ALDH1A1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL21158864 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL8038019 | 0.80 | MC4R (0.51) | ALDH1A1KDM4ETBK1IKBKE | |
| SCHEMBL4553879 | 0.80 | CXCR4 (0.50) | ALDH1A1POLBTDP1HTTHRH3 | |
| SCHEMBL10856726 | 0.79 | KDM4E (0.65) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL15264475 | 0.78 | FAAH (0.52) | ALDH1A1KDM4EFAAHTBK1MEN1 | |
| SCHEMBL5316937 | 0.78 | FAAH (0.67) | ALDH1A1KDM4EHTTFAAHHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |