Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909862 | 0.86 | ALDH1A1 (0.39) | TP53MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL19527508 | 0.85 | TP53 (0.39) | TP53MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL22563994 | 0.83 | MAPT (0.33) | TP53MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL17453761 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2ALMNACYP3A4NPC1 | |
| SCHEMBL19909909 | 0.79 | LMNA (0.37) | TP53MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL28145958 | 0.79 | MEN1 (0.39) | TP53MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL27902968 | 0.79 | GAA (0.39) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL29624292 | 0.79 | SIGMAR1 (0.43) | TP53LMNACYP3A4TRPM8NPC1 | |
| SCHEMBL11592385 | 0.79 | TRPM8 (0.49) | TP53MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL28501086 | 0.79 | LMNA (0.50) | TP53MEN1KMT2ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3020715-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2833889-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-2841433-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |
| CN-101951904-A | Benzothiazole and benzoxazole derivatives and methods of use | ABBOTT LAB | 2011-01-19 | — | — | CN | disclosed |
| CN-1229099-C | Use of reactive dyes for dyeing hair | BASF AG (DE) | 2005-11-30 | — | — | CN | disclosed |
| CN-1351498-A | Pyrrolotriazines inhibitors of kinases | BRISTOL MYERS SQUIBB CO (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1264284-A | Application of reactive dye in hair dyeing | BASF AG (DE) | 2000-08-23 | — | — | CN | disclosed |
| CN-1209744-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-03-03 | — | — | CN | disclosed |