Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195474 | 0.84 | ALOX15 (0.35) | LMNAMAPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL19909972 | 0.84 | NPC1 (0.32) | LMNAMAPTALDH1A1GAAMEN1 | |
| SCHEMBL20902011 | 0.83 | MEN1 (0.38) | LMNAMAPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL22038786 | 0.82 | CTSD (0.43) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18831572 | 0.81 | LMNA (0.33) | LMNAMAPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL22563943 | 0.80 | GAA (0.33) | MAPTGAAP2RX7HSD17B10 | |
| SCHEMBL19909862 | 0.80 | ALDH1A1 (0.39) | LMNAMAPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL19006796 | 0.79 | TP53 (0.39) | LMNAMAPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL20342686 | 0.79 | P2RX7 (0.35) | LMNAMAPTALDH1A1CYP3A4GAA | |
| SCHEMBL18435260 | 0.79 | CYP1A2 (0.40) | ALDH1A1CYP3A4MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |
| EP-3025585-B1 | PLANT DISEASE CONTROL COMPOSITION AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2018-02-28 | — | — | EP | disclosed |