SCHEMBL19909862

SCHEMBL19909862

Cc1cccc(N(N)C(=O)NN)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
LMNA P02545 5/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 4/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPK1 P28482 2/20 0.38
TSHR P16473 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TP53 P04637 3/20 0.37
TRPA1 O75762 2/20 0.35
ATM Q13315 1/20 0.35
CYP3A4 P08684 2/20 0.35
AKR1B10 O60218 1/20 0.35
ABCB11 O95342 1/20 0.35
DHFR P00374 1/20 0.35
MPO P05164 1/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM1 P11229 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19006796 0.86 TP53 (0.39) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL20686606 0.83 HSD17B1 (0.38) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL20195488 0.83 LMNA (0.43) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL19904127 0.83 ALDH1A1 (0.33) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL22563994 0.83 MAPT (0.33) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL18831312 0.81 CTSD (0.44) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL17453761 0.80 ALDH1A1 (0.37) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL19909909 0.80 LMNA (0.37) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL27758851 0.80 TTR (0.38) CYP1A2P2RX7
SCHEMBL20342849 0.80 TAS2R14 (0.42) ALDH1A1LMNAMAPTPTGS1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
EP-3025585-B1 PLANT DISEASE CONTROL COMPOSITION AND ITS USE SUMITOMO CHEMICAL CO (JP) 2018-02-28 EP disclosed
CN-101384303-B Coloring agent for coloring keratin fibers WELLA AG 2012-07-04 CN disclosed