Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | USP5 | P45974 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL461155 | 0.81 | TYR (0.55) | CYP2C9CYP2D6HIF1AKDM4EMAPK1 | |
| Hydrogen Peroxide SCHEMBL182135 | 0.81 | TYR (0.55) | CYP2C9CYP2D6HIF1AKDM4EMAPK1 | |
| Hydrogen Peroxide SCHEMBL20915049 | 0.81 | TYR (0.55) | CYP2C9CYP2D6HIF1AKDM4EMAPK1 | |
| SCHEMBL11417507 | 0.81 | TDP1 (0.45) | CYP2D6HIF1AKDM4EMAPK1POLB | |
| SCHEMBL9494308 | 0.80 | SRC (0.61) | CYP2C9CYP2D6HIF1AKDM4EMAPK1 | |
| SCHEMBL6551674 | 0.80 | PTGS2 (0.65) | CYP2C9CYP2D6HIF1AKDM4EMAPK1 | |
| SCHEMBL4651605 | 0.80 | PTGS2 (0.65) | CYP2C9CYP2D6HIF1AKDM4EMAPK1 | |
| SCHEMBL1502454 | 0.80 | ALDH1A1 (0.48) | POLBSMN1; SMN2CNR2LMNAMEN1 | |
| SCHEMBL467546 | 0.80 | HDAC4 (0.59) | CYP2C9CYP2D6POLBCNR2LMNA | |
| SCHEMBL4761563 | 0.80 | CNR2 (0.47) | CYP2C9CYP2D6HIF1AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172970-A1 | VECTOR DELIVERY-BASED MICROBICIDES | RUSH UNIVERSITY MEDICAL CENTER (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172970-A1 | VECTOR DELIVERY-BASED MICROBICIDES | NOX1, NOS1, NOS2 | CYP2C9 844/4885CYP2D6 987/4885HIF1A 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.