SCHEMBL190072

SCHEMBL190072

O=Cc1cccc(CBr)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
MAOA P21397 7/20 0.49
MAOB P27338 7/20 0.49
UNG P13051 1/20 0.44
TRPA1 O75762 1/20 0.42
TSHR P16473 1/20 0.42
CYP2A6 P11509 1/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
SRC P12931 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
FFAR1 O14842 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29607567 1.00 ALDH1A1 (0.54) ALDH1A1MAOAMAOBUNGTRPA1
SCHEMBL27780984 0.83 ALDH1A1 (0.50) ALDH1A1MAOAMAOBUNGCYP2A6
SCHEMBL6852425 0.82 ALDH1A1 (0.52) ALDH1A1MAOAMAOBUNGCYP2A6
SCHEMBL9079801 0.80 MAOA (0.50) ALDH1A1MAOAMAOBUNGCYP2A6
Benzyl Bromide SCHEMBL30423789 0.80 ALDH1A1 (0.64) ALDH1A1MAOAMAOBUNGTRPA1
SCHEMBL31139357 0.80 MAOB (0.74) ALDH1A1MAOAMAOBNPC1RAB9A
SCHEMBL20233485 0.79 ALDH1A1 (0.46) ALDH1A1MAOAMAOBUNGCYP2A6
SCHEMBL13536780 0.79 DRD1 (0.47) ALDH1A1TRIM24TRIM33CA12CA1
SCHEMBL6406763 0.79 ACHE (0.47) ALDH1A1MAOAMAOBCYP2A6
SCHEMBL417837 0.78 MAOA (0.58) ALDH1A1MAOAMAOBUNGCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359494-A Fluorescent probe capable of specifically recognizing lysine and preparation method thereof 海南大学 2024-07-19 CN claimed
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECH LIMITED (GB) 2026-05-21 US disclosed
US-12559506-B2 Indazole based compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
EP-4692085-A2 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS Nxera Pharma UK Limited (GB) 2026-02-11 EP disclosed
US-20260015314-A1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS NXERA PHARMA UK LTD (GB) 2026-01-15 US disclosed
EP-4041388-B1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS NXERA PHARMA UK LTD (GB) 2025-11-26 EP disclosed
US-20250353874-A1 GLUCOCORTICOID RECEPTOR AGONISTS LILLY CO ELI (US) 2025-11-20 US disclosed
US-20250339406-A1 NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-11-06 US disclosed
EP-4612149-A1 PYRIDO[2,3-D]PYRIMIDIN-2-AMINE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER Cancer Research Technology Limited (GB) 2025-09-10 EP disclosed
EP-4612148-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER Cancer Research Technology Limited (GB) 2025-09-10 EP disclosed
WO-1994019352-A1 MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) 1994-09-01 WO disclosed
US-5306728-A Substituted amine derivatives having antihyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US disclosed
EP-0548235-A1 SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-30 EP disclosed
US-5217966-A Synthetic drug molecules that mimic metalloenzymes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-08 US disclosed
US-5202317-A SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-04-13 US disclosed
WO-1992005178-A1 SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-04-02 WO disclosed
EP-0448078-A2 Substituted amine derivatives having anti-hyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-25 EP disclosed
US-4389410-A Esters of monic acid A useful as antibacterial and antimycoplasmal agents BEECHAM GROUP LIMITED (GB) 1983-06-21 US disclosed
EP-0045150-A1 Antibacterial compounds, processes for their preparation and composititions containing them BEECHAM GROUP PLC (GB) 1982-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER EGFR, KRAS, O60361 ALDH1A1 999/4885MAOA 3706/4885MAOB 2808/4885
US-20250353874-A1 GLUCOCORTICOID RECEPTOR AGONISTS NR3C1, NR3C2, MC2R ALDH1A1 3227/4885MAOA 3267/4885MAOB 3343/4885
US-12559506-B2 Indazole based compounds and associated methods of use LRRK2, CRBN, CLK2 ALDH1A1 3579/4885MAOA 2166/4885MAOB 2303/4885
US-20250339406-A1 NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH NSD3, NSD2, NSD1 ALDH1A1 3591/4885MAOA 4166/4885MAOB 3769/4885
US-20260015314-A1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS PTGER4, PTGER1, PTGER3 ALDH1A1 2468/4885MAOA 2505/4885MAOB 1858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.