Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17035034 | 0.87 | TOP1 (0.33) | TOP1DHODH | |
| SCHEMBL17300246 | 0.85 | DHFR (0.39) | TOP1DHODHDHFR | |
| SCHEMBL17300241 | 0.85 | DHFR (0.40) | DHODHDHFR | |
| SCHEMBL19009861 | 0.83 | MAPT (0.33) | TOP1 | |
| SCHEMBL19009824 | 0.83 | TOP1 (0.33) | TOP1DHODH | |
| SCHEMBL19009769 | 0.82 | TOP1 (0.39) | TOP1DHODHCNR2 | |
| SCHEMBL17300243 | 0.81 | DHODH (0.36) | DHODHDHFR | |
| SCHEMBL17914776 | 0.80 | DHODH (0.41) | DHODH | |
| SCHEMBL19009807 | 0.80 | LMNA (0.33) | TOP1DHODHDHFR | |
| SCHEMBL17300242 | 0.79 | DHODH (0.39) | DHODHDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170179407-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-22 | — | — | US | disclosed |
| US-20170179407-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170179407-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, CCNT1 | TOP1 898/4885DHODH 1619/4885CNR2 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.