SCHEMBL19009861

SCHEMBL19009861

O=P(c1ccccc1)(c1ccccc1)c1cccc(-c2nc3ccccc3c3c4ccccc4c4ccccc4c23)n1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
TOP2A P11388 1/20 0.31
TOP1 P11387 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19051769 0.88 TOP2A (0.34) TOP2ATOP1
SCHEMBL19009849 0.86 MEN1 (0.34) MAPTTOP2ACYP1A2
SCHEMBL19009802 0.83 TOP1 (0.34) TOP1
SCHEMBL18201297 0.83 CYP2C9 (0.32) MAPT
SCHEMBL19009819 0.81 TYMS (0.33) TOP1
SCHEMBL19009824 0.79 TOP1 (0.33) TOP1
SCHEMBL18748101 0.78 LMNA (0.34) MAPTTOP2A
SCHEMBL19009860 0.78 TGFBR1 (0.32) MAPT
SCHEMBL19009859 0.78 ALDH1A1 (0.31) CYP1A2
SCHEMBL17300231 0.77 DHODH (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 MAPT 1824/4885TOP2A 2161/4885TOP1 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.