SCHEMBL19011063

SCHEMBL19011063

Cc1cc(-c2ccccc2)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.54
▸ GGPS1 O95749 1/20 0.45
▸ PTGES2 Q9H7Z7 1/20 0.42
▸ PRKDC P78527 5/20 0.40
▸ PLA2G2A P14555 1/20 0.38
▸ PLA2G4A P47712 1/20 0.38
▸ ATM Q13315 2/20 0.38
▸ PRMT5 O14744 1/20 0.37
▸ WDR77 Q9BQA1 1/20 0.37
▸ NPC1 O15118 2/20 0.36
▸ HPGD P15428 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ AHR P35869 1/20 0.36
▸ GABRP O00591 1/20 0.36
▸ GABRD O14764 1/20 0.36
▸ CA12 O43570 1/20 0.36
▸ TNKS O95271 1/20 0.36
▸ CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12969274 0.93 ALOX5 (0.56) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL1687976 0.92 ALOX5 (0.60) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL17974231 0.92 ALOX5 (0.60) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL18199557 0.91 ALOX5 (0.63) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL12996517 0.91 ALOX5 (0.59) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL12799898 0.91 ALOX5 (0.59) ALOX5GGPS1PTGES2PRKDCATM
SCHEMBL17562031 0.90 ALOX5 (0.58) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL18199556 0.89 ALOX5 (0.61) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL16547046 0.89 ALOX5 (0.49) ALOX5GGPS1PTGES2PRKDCATM
SCHEMBL18960986 0.87 ALOX5 (0.53) ALOX5GGPS1PTGES2PRKDCPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 — — US disclosed
US-20230276691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-31 — — US disclosed
US-20230200211-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 — — US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 — — US disclosed
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 — — US disclosed
WO-2017102064-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 ALOX5 2702/4885GGPS1 1501/4885PTGES2 2410/4885
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, MCOLN3 ALOX5 1527/4885GGPS1 2792/4885PTGES2 2382/4885
US-20230200211-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OPRM1, OCIAD1 ALOX5 1064/4885GGPS1 3797/4885PTGES2 1739/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 ALOX5 2446/4885GGPS1 2492/4885PTGES2 3749/4885
US-20230276691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MCOLN2, LOXL1, LOXL2 ALOX5 171/4885GGPS1 2976/4885PTGES2 402/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 ALOX5 2625/4885GGPS1 1535/4885PTGES2 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback