Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitro Cresol SCHEMBL560751 | 0.89 | GPR35 (0.71) | ALDH1A1GPR35TSHRCES2CES1 | |
| Dinitro Cresol SCHEMBL10684761 | 0.89 | GPR35 (0.71) | ALDH1A1GPR35CES2CES1MAPT | |
| Dinitro Cresol SCHEMBL1716451 | 0.85 | GPR35 (0.93) | ALDH1A1GPR35TSHRMAPTKDM4E | |
| Dinitro Cresol SCHEMBL7991585 | 0.85 | GPR35 (0.73) | ALDH1A1GPR35TSHRMAPTKDM4E | |
| Dinitro Cresol SCHEMBL1509581 | 0.84 | GPR35 (0.78) | ALDH1A1GPR35TSHRMAPTKDM4E | |
| Dinitro Cresol SCHEMBL892354 | 0.84 | ALDH1A1 (0.78) | ALDH1A1GPR35TSHRCES2CES1 | |
| Dinitro Cresol SCHEMBL3976321 | 0.84 | GPR35 (0.78) | ALDH1A1GPR35TSHRMAPTKDM4E | |
| Dinitro Cresol SCHEMBL2549698 | 0.84 | GPR35 (0.89) | ALDH1A1GPR35TSHRMAPTKDM4E | |
| Dinitro Cresol SCHEMBL6859521 | 0.84 | GPR35 (0.96) | ALDH1A1GPR35TSHRMAPTKDM4E | |
| Dinitro Cresol SCHEMBL9221013 | 0.83 | ALDH1A1 (0.81) | ALDH1A1GPR35TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789473-A1 | HIGH PURITY, HIGH MOLECULAR WEIGHT METHOXY-POLYETHYLENGLYCOLS (MPEG) | Dow Gloval Technologies Inc. (US) | 2007-05-30 | — | — | EP | claimed |
| WO-2006028745-A1 | HIGH PURITY, HIGH MOLECULAR WEIGHT METHOXY-POLYETHYLENGLYCOLS (MPEG) | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-03-16 | — | — | WO | claimed |
| US-20060045866-A1 | Novel high purity and high molecular weight mPEG alcohol compositions | CHAPPELOW CHRIS | 2006-03-02 | — | — | US | claimed |
| US-20110109855-A1 | POLYAMIC ACID AND A POLYIMIDE OBTAINED BY REACTING A DIANHYDRIDE AND A DIAMINE | SONY CORPORATION (JP) | 2011-05-12 | — | — | US | disclosed |