Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Dinitro Cresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitro Cresol SCHEMBL10684761 | 0.91 | GPR35 (0.71) | GPR35ALDH1A1MAPTCES2CES1 | |
| Dinitro Cresol SCHEMBL1901668 | 0.89 | ALDH1A1 (0.68) | GPR35ALDH1A1TSHRMAPTCES2 | |
| Dinitro Cresol SCHEMBL1716451 | 0.88 | GPR35 (0.93) | GPR35ALDH1A1TSHRMAPTTP53 | |
| Dinitro Cresol SCHEMBL1509581 | 0.87 | GPR35 (0.78) | GPR35ALDH1A1TSHRMAPTTP53 | |
| Dinitro Cresol SCHEMBL892354 | 0.87 | ALDH1A1 (0.78) | GPR35ALDH1A1TSHRMAPTCES2 | |
| Dinitro Cresol SCHEMBL3976321 | 0.87 | GPR35 (0.78) | GPR35ALDH1A1TSHRMAPTTP53 | |
| Dinitro Cresol SCHEMBL2549698 | 0.86 | GPR35 (0.89) | GPR35ALDH1A1TSHRMAPTTP53 | |
| Dinitro Cresol SCHEMBL6859521 | 0.86 | GPR35 (0.96) | GPR35ALDH1A1TSHRMAPTTP53 | |
| Dinitro Cresol SCHEMBL9221013 | 0.85 | ALDH1A1 (0.81) | GPR35ALDH1A1TSHRMAPTTP53 | |
| Dinitro Cresol SCHEMBL4735684 | 0.85 | GPR35 (0.81) | GPR35ALDH1A1TSHRMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114291992-B | Preparation combination for removing municipal sludge antibiotic resistance genes and application | 华中师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114291992-A | Preparation combination for removing municipal sludge antibiotic resistance genes and application | 华中师范大学 | 2022-04-08 | — | — | CN | claimed |
| CN-110047656-A | Middle jewelling electrolytic capacitor low-leakage current Working electrolyte and preparation method thereof | 益阳市开元电子有限公司 | 2019-07-23 | — | — | CN | claimed |
| US-7642057-B2 | Method and probes for the detection of chromosome aberrations | DAKO DENMARK A/S (DK) | 2010-01-05 | — | — | US | claimed |
| US-20090120545-A1 | Infra-Red Decoy Flare | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETEN-SCHAPPELIJK ONDERZOEK TNO (NL) | 2009-05-14 | — | — | US | claimed |
| US-7368245-B2 | Method and probes for the detection of chromosome aberrations | DAKO DENMARK A/S (DK) | 2008-05-06 | — | — | US | claimed |
| EP-1904421-A2 | AN INFRA-RED DECOY FLARE | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO (NL) | 2008-04-02 | — | — | EP | claimed |
| EP-0862650-B1 | IN SITU HYBRIDIZATION TO DETECT SPECIFIC NUCLEIC ACID SEQUENCES IN EUCARYOTIC SAMPLES | DAKO DENMARK AS (DK) | 2007-08-01 | — | — | EP | claimed |
| WO-2007004871-A2 | AN INFRA-RED DECOY FLARE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-01-11 | — | — | WO | claimed |
| US-20060160106-A1 | Using peptide nucleic acid probes to detect chromosome aberrations in eukaryotic cells | DAKO A/S (DK) | 2006-07-20 | — | — | US | claimed |
| US-5985563-A | DETECTING SEXUAL TRANSMITTED DISEASES | DAKO A/S (DK) | 1999-11-16 | — | — | US | claimed |
| WO-1999057309-A1 | METHOD AND PROBES FOR THE DETECTION OF CHROMOSOME ABERRATIONS | DAKO A/S (DK) | 1999-11-11 | — | — | WO | claimed |
| US-5888733-A | DETECTING THE PRESENCE OF SPECIFIC RNA SEQUENCES IN A SAMPLE; DIAGNOSING DISEASES SUCH AS BACTERIAL AND VIRAL INFECTIONS, GENETIC DSEASES AND NEOPLASTIC DISORDERS | DAKO A/S (DK) | 1999-03-30 | — | — | US | claimed |
| EP-0862650-A1 | IN SITU HYBRIDIZATION TO DETECT SPECIFIC NUCLEIC ACID SEQUENCES IN EUCARYOTIC SAMPLES | DAKO A/S (DK) | 1998-09-09 | — | — | EP | claimed |
| EP-0835449-A1 | METHOD FOR THE SIMULTANEOUS DETECTION OF DIFFERENT ANTIBODIES AND/OR ANTIGENS | DAKO A/S (DK) | 1998-04-15 | — | — | EP | claimed |
| WO-1997018325-A1 | IN SITU HYBRIDIZATION TO DETECT SPECIFIC NUCLEIC ACID SEQUENCES IN EUCARYOTIC SAMPLES | DAKO A/S (DK) | 1997-05-22 | — | — | WO | claimed |
| EP-0760008-A1 | PNA PROBES FOR DETECTION OF NEISSERIA GONORRHOEAE AND CHLAMYDIA TRACHOMATIS | DAKO A/S (DK) | 1997-03-05 | — | — | EP | claimed |
| WO-1997001758-A1 | METHOD FOR THE SIMULTANEOUS DETECTION OF DIFFERENT ANTIBODIES AND/OR ANTIGENS | DAKO A/S (DK) | 1997-01-16 | — | — | WO | claimed |
| WO-1995032305-A1 | PNA PROBES FOR DETECTION OF NEISSERIA GONORRHOEAE AND CHLAMYDIA TRACHOMATIS | DAKO A/S (DK) | 1995-11-30 | — | — | WO | claimed |
| US-4049457-A | WITH AN ORGANIC ACID | BARD LABORATORIES, INC. (US) | 1977-09-20 | — | — | US | claimed |