Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149348 | 0.90 | ALDH1A1 (0.73) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL232188 | 0.89 | MAPT (0.78) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL18660177 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL18660198 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL18660199 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL19018359 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL809568 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL11655423 | 0.86 | RECQL (0.61) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL6416019 | 0.86 | MAPT (0.74) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR | |
| SCHEMBL1562142 | 0.86 | MAPT (0.74) | ALDH1A1HSD17B10L3MBTL1ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634939-B1 | METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEM CO (US) | 2021-03-24 | — | — | EP | disclosed |
| EP-3792245-A1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | Eastman Chemical Company (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3394028-B1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | EASTMAN CHEM CO (US) | 2020-11-04 | — | — | EP | disclosed |
| US-10611719-B2 | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy | EASTMAN CHEMICAL COMPANY (US) | 2020-04-07 | — | — | US | disclosed |
| US-10611719-B2 | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy | EASTMAN CHEMICAL COMPANY (US) | 2020-04-07 | — | — | US | disclosed |
| US-10428009-B2 | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy | EASTMAN CHEMICAL COMPANY (US) | 2019-10-01 | — | — | US | disclosed |
| US-10428009-B2 | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy | EASTMAN CHEMICAL COMPANY (US) | 2019-10-01 | — | — | US | disclosed |
| US-10407562-B2 | Compounds with antidegradant and antifatigue efficacy and compositions including said compounds | EASTMAN CHEMICAL COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| US-10287418-B2 | Compounds with antidegradant and antifatigue efficacy and compositions including said compounds | EASTMAN CHEMICAL COMPANY (US) | 2019-05-14 | — | — | US | disclosed |
| US-10260017-B2 | Compounds and mixtures with antidegradant and antifatigue efficacy and compositions including said compounds | EASTMAN CHEMICAL COMPANY (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170275237-A1 | COMPOUNDS AND MIXTURES WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275233-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275234-A1 | METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275238-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275233-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | EASTMAN CHEMICAL COMPANY (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2017112440-A1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2017-06-29 | — | — | WO | disclosed |
| US-20170174615-A1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275237-A1 | COMPOUNDS AND MIXTURES WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | ACHE, CCNE2, CHRM1 | ALDH1A1 1291/4885HSD17B10 1079/4885L3MBTL1 2556/4885 |
| US-10428009-B2 | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy | ACHE, DDO, BCHE | ALDH1A1 790/4885HSD17B10 845/4885L3MBTL1 2553/4885 |
| US-10611719-B2 | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy | ACHE, DDO, BCHE | ALDH1A1 790/4885HSD17B10 845/4885L3MBTL1 2553/4885 |
| US-20170275234-A1 | METHODS OF MAKING COMPOUNDS HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | ACHE, HNMT, PNMT | ALDH1A1 603/4885HSD17B10 495/4885L3MBTL1 2029/4885 |
| US-10260017-B2 | Compounds and mixtures with antidegradant and antifatigue efficacy and compositions including said compounds | ACHE, CCNE2, CHRM1 | ALDH1A1 1291/4885HSD17B10 1079/4885L3MBTL1 2556/4885 |
| US-20170275238-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | ACHE, BCHE, DDO | ALDH1A1 730/4885HSD17B10 664/4885L3MBTL1 2559/4885 |
| US-20170174615-A1 | COMPOUNDS WITH ANTIDEGRADANT AND ANTIFATIGUE EFFICACY AND COMPOSITIONS INCLUDING SAID COMPOUNDS | ACHE, HDAC3, PON1 | ALDH1A1 1067/4885HSD17B10 860/4885L3MBTL1 2609/4885 |
| US-10407562-B2 | Compounds with antidegradant and antifatigue efficacy and compositions including said compounds | ACHE, HDAC3, PON1 | ALDH1A1 1067/4885HSD17B10 860/4885L3MBTL1 2609/4885 |
| US-20170275233-A1 | METHODS OF MAKING COMPOUNDS AND MIXTURES HAVING ANTIDEGRADANT AND ANTIFATIGUE EFFICACY | ACHE, DDO, BCHE | ALDH1A1 790/4885HSD17B10 845/4885L3MBTL1 2553/4885 |
| US-10287418-B2 | Compounds with antidegradant and antifatigue efficacy and compositions including said compounds | ACHE, HDAC3, PON1 | ALDH1A1 1067/4885HSD17B10 860/4885L3MBTL1 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.