Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913605 | 0.83 | TDP1 (0.42) | SLC6A4SLC6A3ALDH1A1SLC6A2SCN10A | |
| SCHEMBL14625259 | 0.81 | SLC6A3 (0.47) | SLC6A4SLC6A3SLC6A2SCN10AOPRD1 | |
| SCHEMBL4745351 | 0.78 | HDAC3 (0.40) | SLC6A4SLC6A3SLC6A2ESR2 | |
| SCHEMBL24746321 | 0.76 | ABCC9 (0.36) | SLC6A4SLC6A3SLC6A2OPRD1 | |
| SCHEMBL12021962 | 0.76 | DRD2 (0.36) | SLC6A4SLC6A3OPRD1LMNAMAPT | |
| SCHEMBL14625193 | 0.76 | SLC6A3 (0.51) | SLC6A4SLC6A3ALDH1A1SLC6A2LMNA | |
| SCHEMBL9104504 | 0.75 | TDP1 (0.39) | SLC6A4SLC6A3ALDH1A1SLC6A2SCN10A | |
| SCHEMBL12898001 | 0.73 | AKR1B10 (0.45) | SLC6A4SLC6A3SLC6A2OPRD1MAPT | |
| SCHEMBL257534 | 0.73 | SLC6A3 (0.49) | SLC6A4SLC6A3SLC6A2OPRD1 | |
| SCHEMBL1931993 | 0.72 | CCR2 (0.34) | SLC6A4SLC6A3SLC6A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493845-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051165-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | WO | disclosed |