Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061947 | 0.84 | P2RX7 (0.44) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL19061872 | 0.81 | MAPK1 (0.41) | ALDH1A1SMN1; SMN2MAPK1GAATDP1 | |
| SCHEMBL19061440 | 0.79 | MAPK1 (0.46) | ALDH1A1SMN1; SMN2MAPK1GAATDP1 | |
| SCHEMBL19019922 | 0.79 | MAPK1 (0.50) | ALDH1A1KMT2ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL22263152 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL22263137 | 0.78 | MAPK1 (0.50) | ALDH1A1KMT2AMAPK1MEN1THRB | |
| SCHEMBL20917965 | 0.78 | MAPK1 (0.41) | ALDH1A1KMT2ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL22263119 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPK1 | |
| SCHEMBL20917786 | 0.76 | ALOX15B (0.46) | ALDH1A1MAPK1GAAL3MBTL1 | |
| SCHEMBL19019923 | 0.76 | GAA (0.43) | ALDH1A1KMT2ASMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |