Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019864 | 0.93 | GFER (0.53) | GFERTSHRKDM4EHSD17B10MEN1 | |
| SCHEMBL19019921 | 0.91 | PKM (0.48) | GFERTSHRKDM4EHSD17B10MEN1 | |
| SCHEMBL19019922 | 0.84 | MAPK1 (0.50) | KDM4EHSD17B10MEN1KMT2ATRPV6 | |
| SCHEMBL19062034 | 0.84 | GFER (0.44) | GFERKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19061954 | 0.84 | HSD17B10 (0.42) | GFERKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19019915 | 0.84 | TRPV6 (0.61) | GFERKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19062036 | 0.83 | POLB (0.44) | GFERKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19061885 | 0.83 | MEN1 (0.52) | KDM4EHSD17B10MEN1KMT2ATRPV6 | |
| SCHEMBL19061883 | 0.83 | MEN1 (0.48) | GFERKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19061887 | 0.81 | L3MBTL1 (0.51) | TSHRHSD17B10MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |