Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061876 | 0.91 | GFER (0.47) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19019864 | 0.90 | GFER (0.53) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19061883 | 0.88 | MEN1 (0.48) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19019922 | 0.88 | MAPK1 (0.50) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19061892 | 0.87 | MMP1 (0.43) | PKMALDH1A1TSHRHSD17B10CHRNB2 | |
| SCHEMBL14286352 | 0.86 | OPRK1 (0.48) | PKMMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL19019834 | 0.86 | PLA2G7 (0.47) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19019870 | 0.86 | CHRNB2 (0.43) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19061740 | 0.85 | NPC1 (0.46) | PKMALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL19061881 | 0.85 | TP53 (0.47) | ALDH1A1RAB9ASMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |