Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061883 | 0.89 | MEN1 (0.48) | MEN1KMT2ATHRBHSD17B10PKM | |
| SCHEMBL19061459 | 0.87 | RAB9A (0.46) | MEN1KMT2AHSD17B10PKMKDM4E | |
| SCHEMBL19061887 | 0.87 | L3MBTL1 (0.51) | MEN1KMT2AHSD17B10PKMLMNA | |
| SCHEMBL19019917 | 0.87 | TDP1 (0.46) | MEN1KMT2AHSD17B10PKMTRPV6 | |
| SCHEMBL19019864 | 0.86 | GFER (0.53) | MEN1KMT2AHSD17B10PKMTRPV6 | |
| SCHEMBL19019922 | 0.86 | MAPK1 (0.50) | MEN1KMT2AHSD17B10PKMTRPV6 | |
| SCHEMBL19062032 | 0.84 | MAPT (0.46) | MEN1KMT2AHSD17B10PKMALDH1A1 | |
| SCHEMBL19061464 | 0.84 | GSK3A (0.41) | MEN1KMT2AHSD17B10PKMALDH1A1 | |
| SCHEMBL19061599 | 0.84 | KDM4E (0.53) | HSD17B10PKMKDM4EALDH1A1GRIN1 | |
| SCHEMBL19061952 | 0.84 | CYP1A2 (0.51) | MEN1KMT2AHSD17B10PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |