Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062011 | 0.86 | ALDH1A1 (0.46) | KDM4EMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL19061440 | 0.83 | MAPK1 (0.46) | KDM4EMAPK1ALDH1A1GAA | |
| SCHEMBL19019884 | 0.83 | MAPT (0.43) | MAPK1MAPTGAA | |
| SCHEMBL19019870 | 0.77 | CHRNB2 (0.43) | KDM4EMAPK1ALDH1A1POLBMEN1 | |
| SCHEMBL19019882 | 0.74 | TRPV6 (0.43) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL19061725 | 0.74 | MAPK1 (0.35) | KDM4EMAPK1MAPT | |
| SCHEMBL19061947 | 0.74 | P2RX7 (0.44) | MAPK1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL22275605 | 0.73 | CYP1A2 (0.38) | MAPK1MEN1KMT2AMAPT | |
| SCHEMBL19019923 | 0.73 | GAA (0.43) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL22263119 | 0.73 | ALDH1A1 (0.43) | MAPK1ALDH1A1MEN1KMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |