Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061728 | 0.92 | USP2 (0.51) | MAPTHPGDTP53RXFP1MEN1 | |
| SCHEMBL19061885 | 0.84 | MEN1 (0.52) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL19061479 | 0.84 | THRB (0.39) | MAPTHPGDTP53MEN1KMT2A | |
| SCHEMBL19061883 | 0.77 | MEN1 (0.48) | HPGDMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL19019922 | 0.74 | MAPK1 (0.50) | MEN1KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19062024 | 0.74 | PKM (0.45) | MEN1KMT2ATSHRLMNAHSD17B10 | |
| SCHEMBL19061471 | 0.73 | CYP1A2 (0.40) | MAPTHPGDTP53MEN1KMT2A | |
| SCHEMBL19061887 | 0.73 | L3MBTL1 (0.51) | MAPTMEN1KMT2AUSP2TSHR | |
| SCHEMBL19061452 | 0.73 | PKM (0.48) | MEN1KMT2ASMN1; SMN2HTTHSD17B10 | |
| SCHEMBL19061459 | 0.73 | RAB9A (0.46) | MAPTHPGDTP53RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |