Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061954 | 0.92 | HSD17B10 (0.42) | RAB9ASMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL19019870 | 0.89 | CHRNB2 (0.43) | RAB9ASMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL19062037 | 0.88 | METAP2 (0.43) | ALDH1A1KMT2AMAPTGFERKDM4E | |
| SCHEMBL19061887 | 0.87 | L3MBTL1 (0.51) | RAB9AKMT2AMAPTLMNAGRIN1 | |
| SCHEMBL19061885 | 0.87 | MEN1 (0.52) | ALDH1A1KMT2AKDM4ELMNAHPGD | |
| SCHEMBL19019917 | 0.87 | TDP1 (0.46) | ALDH1A1KMT2AKDM4EHPGDPKM | |
| SCHEMBL19061947 | 0.86 | P2RX7 (0.44) | RAB9ASMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL19061599 | 0.86 | KDM4E (0.53) | RAB9AALDH1A1GFERKDM4EGRIN1 | |
| SCHEMBL19062035 | 0.86 | HSD17B10 (0.40) | ALDH1A1KMT2AMAPTGFERKDM4E | |
| SCHEMBL19019922 | 0.86 | MAPK1 (0.50) | RAB9ASMN1; SMN2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |