SCHEMBL1906641

SCHEMBL1906641

O=C(O)C(O)Cc1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.56
CPA1 P15085 1/20 0.53
PPARG P37231 2/20 0.49
PPARA Q07869 2/20 0.49
ALDH1A1 P00352 1/20 0.46
TRPA1 O75762 1/20 0.46
FFAR1 O14842 1/20 0.44
ACE P12821 1/20 0.44
KMT2A Q03164 1/20 0.43
CTBP2 P56545 1/20 0.43
MME P08473 1/20 0.42
CA2 P00918 1/20 0.42
TPH1 P17752 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8953439 1.00 KDM6B (0.56) KDM6BCPA1PPARGPPARAALDH1A1
SCHEMBL2769600 1.00 KDM6B (0.56) KDM6BCPA1PPARGPPARAALDH1A1
SCHEMBL1906640 1.00 KDM6B (0.56) KDM6BCPA1PPARGPPARAALDH1A1
SCHEMBL18248073 0.94 KDM6B (0.51) KDM6BCPA1PPARGPPARAALDH1A1
SCHEMBL28815028 0.94 KDM6B (0.51) KDM6BCPA1PPARGPPARAALDH1A1
SCHEMBL10891346 0.89 KDM6B (0.67) KDM6BACEMME
SCHEMBL754625 0.83 LDHA (0.57) CPA1PPARGPPARAALDH1A1TRPA1
SCHEMBL1907744 0.82 EPHX1 (0.45) CPA1PPARGPPARATRPA1
SCHEMBL5807390 0.82 TRPA1 (0.48) KDM6BCPA1PPARGPPARATRPA1
SCHEMBL235131 0.81 KDM6B (0.63) KDM6BACEMMECA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
EP-1639119-B1 METHOD FOR THE MICROBIOLOGICAL ISOMERISATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS BASF SE (DE) 2010-04-21 EP claimed
EP-1639119-A1 METHOD FOR THE MICROBIOLOGICAL ISOMERISATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 2006-03-29 EP claimed
WO-2004111257-A1 METHOD FOR THE MICROBIOLOGICAL ISOMERISATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 2004-12-23 WO claimed
US-20230331734-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2023-10-19 US disclosed
WO-2023196307-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. (US) 2023-10-12 WO disclosed
CN-114891070-A Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-08-12 CN disclosed
US-11382949-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2022-07-12 US disclosed
CN-107835818-B Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-04-29 CN disclosed
US-10793604-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2020-10-06 US disclosed
CN-110167921-A ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS 勃林格殷格翰动物保健美国公司 2019-08-23 CN disclosed
CN-105980387-B Serine/threonine kinase inhibitor 阵列生物制药公司 2019-04-19 CN disclosed
EP-0634408-B1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO (JP) 2002-01-02 EP disclosed
EP-1073672-A1 ANTIPICORNAVIRAL COMPOUNDS, THEIR PREPARATION AND USE AGOURON PHARMACEUTICALS, INC. (US) 2001-02-07 EP disclosed
WO-1999057135-A1 ANTIPICORNAVIRAL COMPOUNDS, THEIR PREPARATION AND USE AGOURON PHARMACEUTICALS, INC. (US) 1999-11-11 WO disclosed
CN-1039331-C Depsispeptide derivative, preparation and application of same FUJISAMA PHARMACEUTICAL CO LTD (JP) 1998-07-29 CN disclosed
US-5679671-A ANGIOTENSIN 1-CONVERTING ENZYME INHIBITOR, VASOPRESSIN ANTAGONISM AND ATRIAL NAUTRIURETIC PEPTIDE HYDROLASE INHIBITOR EISAI CO., LTD. (JP) 1997-10-21 US disclosed
EP-0671172-A1 AMINO ACID DERIVATIVE Eisai Co., Ltd. (JP) 1995-09-13 EP disclosed
EP-0634408-A1 DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-01-18 EP disclosed
CN-1080932-A Depsipeptide derivative and manufacture method thereof and purposes FUJISAWA PHARMACEUTICAL CO (JP) 1994-01-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331734-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ACE, PKD1, ACE2 KDM6B 4705/4885CPA1 334/4885PPARG 2686/4885
US-11382949-B2 Anthelmintic depsipeptide compounds ENPP2, ROCK2, RRP12 KDM6B 2032/4885CPA1 46/4885PPARG 3652/4885
US-10793604-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP KDM6B 1931/4885CPA1 35/4885PPARG 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.