SCHEMBL19069625

SCHEMBL19069625

CC(CCCCNC(=O)CI)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ KMT2A Q03164 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ ACE2 Q9BYF1 1/20 0.41
▸ ITGB3 P05106 1/20 0.40
▸ ITGA2B P08514 1/20 0.40
▸ GABRR1 P24046 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ FOLH1 Q04609 2/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ HPGD P15428 1/20 0.36
▸ ALB P02768 2/20 0.36
▸ TBXAS1 P24557 1/20 0.36
▸ CASP2 P42575 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20900404 0.84 MEN1 (0.63) LTA4HBLMKMT2AMEN1ACE2
SCHEMBL14217283 0.84 MEN1 (0.63) LTA4HBLMKMT2AMEN1ACE2
SCHEMBL16828262 0.82 LTA4H (0.43) LTA4HBLMKMT2AMEN1ACE2
SCHEMBL12413859 0.81 CYP1A2 (0.52) LTA4HBLMKMT2AMEN1ACE2
SCHEMBL19069567 0.81 CASP2 (0.59) LTA4HBLMKMT2AMEN1ACE2
SCHEMBL21261702 0.81 ALDH1A1 (0.43) LTA4HBLMKMT2AMEN1ACE2
SCHEMBL18588225 0.79 KDM4E (0.58) LTA4HBLMACE2ITGB3ITGA2B
SCHEMBL14930734 0.79 KDM4E (0.58) LTA4HBLMACE2ITGB3ITGA2B
SCHEMBL15871482 0.79 FOLH1 (0.43) KMT2AMEN1FOLH1ALB
SCHEMBL20528860 0.79 FOLH1 (0.49) FOLH1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11045523-B2 Formulation of growth hormone albumin-binder conjugate NOVO NORDISK HEALTHCARE AG (CH) 2021-06-29 — — US disclosed
US-20190203213-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTHCARE AG (CH) 2019-07-04 — — US disclosed
US-20170239362-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-08-24 — — US disclosed
US-9695226-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045523-B2 Formulation of growth hormone albumin-binder conjugate ALB, SHBG, SERPINA6 LTA4H 1657/4885BLM 4507/4885KMT2A 3876/4885
US-20170239362-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM LTA4H 1577/4885BLM 2900/4885KMT2A 3466/4885
US-20190203213-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM LTA4H 1577/4885BLM 2900/4885KMT2A 3466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback