SCHEMBL19078772

SCHEMBL19078772

Cc1cnn(C(=O)N2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)c1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17276603 0.88 FAAH (0.52) FAAH
SCHEMBL19078778 0.88 AKR1C3 (0.55) —
SCHEMBL19078776 0.88 L3MBTL1 (0.55) —
SCHEMBL19078775 0.86 AKR1C3 (0.56) —
SCHEMBL19078780 0.85 FAAH (0.54) FAAH
SCHEMBL17276459 0.84 LMNA (0.54) —
SCHEMBL19078731 0.84 ALDH1A1 (0.59) FAAH
SCHEMBL19078738 0.84 L3MBTL1 (0.54) —
SCHEMBL19078746 0.83 KDM4E (0.53) —
SCHEMBL17276610 0.83 FAAH (0.55) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170190669-A1 PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2017-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170190669-A1 PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, FAAH, FAAH2 FAAH 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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