Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078784 | 0.93 | AKR1C3 (0.58) | AKR1C3ALDH1A1LMNAHPGDHTT | |
| SCHEMBL19078794 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTGFERFAAHMGLL | |
| SCHEMBL19078790 | 0.89 | AKR1C3 (0.62) | AKR1C3LMNAMAPT | |
| SCHEMBL19078787 | 0.89 | AKR1C3 (0.56) | AKR1C3ALDH1A1LMNAHPGDHTT | |
| SCHEMBL19078767 | 0.89 | FAAH (0.59) | AKR1C3ALDH1A1FAAHMGLL | |
| SCHEMBL19078774 | 0.88 | — | — | |
| SCHEMBL19078789 | 0.87 | AKR1C3 (0.46) | AKR1C3ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL19078793 | 0.86 | LMNA (0.48) | AKR1C3ALDH1A1LMNAMAPT | |
| SCHEMBL19078756 | 0.85 | NOS1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL19078768 | 0.84 | NOS1 (0.44) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, FAAH, FAAH2 | AKR1C3 1992/4885ALDH1A1 1322/4885LMNA 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.