Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13308118 | 0.85 | CYP4F2 (0.47) | MTNR1AMTNR1BALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL1283948 | 0.85 | CA2 (0.50) | MTNR1AMTNR1BCYP4F2CYP4A11LMNA | |
| SCHEMBL21554546 | 0.85 | CA2 (0.50) | MTNR1AMTNR1BALDH1A1LMNAHPGD | |
| SCHEMBL7517689 | 0.85 | HPGD (0.50) | MTNR1AMTNR1BCYP4F2CYP4A11RIPK1 | |
| SCHEMBL9895432 | 0.83 | CA12 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL5533824 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21880654 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL5866843 | 0.83 | LOXL2 (0.46) | MTNR1AMTNR1BALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL16447010 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL479237 | 0.83 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189390-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC. (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189390-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | BRS3, BDKRB2, NTSR2 | MTNR1A 173/4885MTNR1B 43/4885ALDH1A1 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.