Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088599 | 0.97 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL19088700 | 0.82 | CHRNB2 (0.48) | ALDH1A1KDM4EMAPT | |
| SCHEMBL17276358 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL17276591 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL19088701 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4E | |
| SCHEMBL19078749 | 0.79 | KDM4E (0.57) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL17276415 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL17276478 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL19088721 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL17276509 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, FAAH, FAAH2 | ALDH1A1 1322/4885KDM4E 2168/4885MAPT 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.