Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17281577 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL19078745 | 0.81 | HTT (0.59) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL17281608 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL17281587 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL17276488 | 0.79 | LMNA (0.60) | KDM4ETDP1KMT2AFAAHLMNA | |
| SCHEMBL19088700 | 0.78 | CHRNB2 (0.48) | ALDH1A1KDM4ETDP1HTTMAPT | |
| SCHEMBL27663681 | 0.77 | ALDH1A1 (0.70) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL19088701 | 0.77 | KDM4E (0.48) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL17281600 | 0.77 | KDM4E (0.60) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL19088588 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, FAAH, FAAH2 | ALDH1A1 1322/4885KDM4E 2168/4885TDP1 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.