SCHEMBL19088921 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	RIPK1	Q13546	4/20	0.36

▸	TAS1R3	Q7RTX0	3/20	0.33

▸	TAS1R1	Q7RTX1	3/20	0.33

▸	PDE4D	Q08499	2/20	0.33

▸	PDE4A	P27815	1/20	0.33

▸	PDE4B	Q07343	1/20	0.33

▸	PDE4C	Q08493	1/20	0.33

▸	TAS1R2	Q8TE23	1/20	0.32

▸	MET	P08581	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17417044	0.93	RIPK1 (0.36)	RIPK1TAS1R3TAS1R1PDE4DPDE4A
SCHEMBL19088924	0.93	PDE4D (0.36)	RIPK1PDE4DPDE4APDE4BPDE4C
SCHEMBL17898828	0.92	RIPK1 (0.34)	RIPK1TAS1R3TAS1R1PDE4DPDE4A
SCHEMBL17898782	0.90	RIPK1 (0.33)	RIPK1
SCHEMBL19084210	0.89	TAS1R3 (0.38)	RIPK1TAS1R3TAS1R1TAS1R2
SCHEMBL19088927	0.89	TAS1R3 (0.33)	RIPK1TAS1R3TAS1R1PDE4DPDE4A
SCHEMBL19088922	0.89	RIPK1 (0.35)	RIPK1PDE4DPDE4APDE4BPDE4C
SCHEMBL17418696	0.89	SHBG (0.33)	RIPK1
SCHEMBL17428163	0.89	SHBG (0.33)	RIPK1
SCHEMBL17898893	0.88	IGF1R (0.33)	RIPK1PDE4DPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017116949-A1	MACROCYCLIC PICOLINAMIDES AS FUNGICIDES	DOW AGROSCIENCES LLC (US)	2017-07-06	—	—	WO	disclosed