Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088921 | 0.93 | RIPK1 (0.36) | PDE4DPDE4APDE4BPDE4CRIPK1 | |
| SCHEMBL19084218 | 0.89 | TAS1R3 (0.37) | NAAA | |
| SCHEMBL17428164 | 0.89 | NAAA (0.33) | NAAA | |
| SCHEMBL19088927 | 0.88 | TAS1R3 (0.33) | PDE4DPDE4APDE4BPDE4CRIPK1 | |
| SCHEMBL17417044 | 0.88 | RIPK1 (0.36) | PDE4DPDE4APDE4BPDE4CRIPK1 | |
| SCHEMBL19089227 | 0.87 | PDE4D (0.34) | PDE4DPDE4APDE4BPDE4CRIPK1 | |
| SCHEMBL19088918 | 0.87 | PDE4D (0.34) | PDE4D | |
| SCHEMBL19091511 | 0.87 | PDE4D (0.38) | PDE4DPDE4APDE4BPDE4CNAAA | |
| SCHEMBL19088925 | 0.87 | TAS1R3 (0.31) | RIPK1 | |
| SCHEMBL19091129 | 0.86 | MERTK (0.35) | PDE4DPDE4APDE4BPDE4CNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |