Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428163 | 1.00 | SHBG (0.33) | SHBGRIPK1KMT2ACASP1 | |
| SCHEMBL17428189 | 0.95 | SHBG (0.32) | SHBGRIPK1KMT2A | |
| SCHEMBL17428195 | 0.95 | RIPK1 (0.34) | SHBGRIPK1 | |
| SCHEMBL17428177 | 0.94 | KMT2A (0.32) | RIPK1KMT2A | |
| SCHEMBL17428178 | 0.94 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL17428191 | 0.94 | TAS1R3 (0.31) | RIPK1KMT2ACASP1 | |
| SCHEMBL17428187 | 0.93 | P2RX7 (0.33) | SHBGRIPK1 | |
| SCHEMBL17428186 | 0.93 | NAAA (0.35) | — | |
| SCHEMBL17428176 | 0.93 | CASP1 (0.31) | SHBGRIPK1CASP1 | |
| SCHEMBL20099143 | 0.93 | CASP1 (0.31) | SHBGRIPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180242582-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-08-30 | — | — | US | disclosed |
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| WO-2016007529-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | SHBG 775/4885RIPK1 4127/4885KMT2A 3234/4885 |
| US-20180242582-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | SHBG 775/4885RIPK1 4127/4885KMT2A 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.