Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084208 | 0.90 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2DRD2 | |
| SCHEMBL19089228 | 0.88 | ROCK1 (0.31) | ROCK2ROCK1 | |
| SCHEMBL19088921 | 0.87 | RIPK1 (0.36) | TAS1R3TAS1R1TAS1R2RIPK1 | |
| SCHEMBL19088924 | 0.87 | PDE4D (0.36) | RIPK1 | |
| SCHEMBL19088927 | 0.86 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2RIPK1ROCK2 | |
| SCHEMBL19088918 | 0.85 | PDE4D (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17417044 | 0.84 | RIPK1 (0.36) | TAS1R3TAS1R1TAS1R2RIPK1 | |
| SCHEMBL19088919 | 0.84 | PDE4D (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17898894 | 0.82 | HPGDS (0.32) | TAS1R3TAS1R1TAS1R2RIPK1ROCK2 | |
| SCHEMBL19066904 | 0.82 | GRM4 (0.34) | RIPK1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |