Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | F13A1 | P00488 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349999 | 0.83 | TUBB4A (0.49) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8589506 | 0.82 | MEN1 (0.47) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8867866 | 0.82 | MEN1 (0.47) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8867871 | 0.82 | MEN1 (0.47) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9126056 | 0.81 | MEN1 (0.46) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6992696 | 0.81 | CNR1 (0.45) | KDM4ESMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL25855377 | 0.80 | RAB9A (0.50) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8545207 | 0.80 | NPC1 (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL23126144 | 0.79 | KDM4E (0.50) | KDM4EF13A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19089782 | 0.79 | POLB (0.57) | KDM4EF13A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066526-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-07-20 | — | — | US | disclosed |
| US-11066526-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-07-20 | — | — | US | disclosed |
| US-20190010113-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2019-01-10 | — | — | US | disclosed |
| CN-108884173-A | METHOD FOR CLEAVING AMIDE BONDS | 高德美股份公司 | 2018-11-23 | — | — | CN | disclosed |
| WO-2017114859-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010113-A1 | METHOD FOR CLEAVING AMIDE BONDS | DNPEP, NAAA, ASPH | KDM4E 1693/4885F13A1 1144/4885SMN1; SMN2 3089/4885 |
| US-11066526-B2 | Method for cleaving amide bonds | DNPEP, NAAA, ASPH | KDM4E 1693/4885F13A1 1144/4885SMN1; SMN2 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.