Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17317895 | 0.84 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL17317914 | 0.83 | SIGMAR1 (0.44) | SIGMAR1HTR2AHTR2CHTR7HTR2B | |
| SCHEMBL14784245 | 0.78 | KCNK3 (0.58) | KCNK3 | |
| SCHEMBL19110586 | 0.73 | SLC2A1 (0.48) | SIGMAR1HTR7 | |
| SCHEMBL10799585 | 0.72 | KCNK3 (0.53) | KCNK3 | |
| SCHEMBL19110582 | 0.68 | KCNK3 (0.50) | KCNK3 | |
| SCHEMBL16088518 | 0.66 | SOD3 (0.36) | HTR2AHTR2C | |
| SCHEMBL16118495 | 0.65 | HTR2A (0.38) | HTR2AHTR2CHTR7HTR2B | |
| SCHEMBL19110601 | 0.65 | ALDH1A1 (0.42) | HTR2AHTR2CHTR7HTR2B | |
| SCHEMBL16089630 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | BIOGEN MA INC. | 2017-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197960-A1 | ATX MODULATING AGENTS | ENPP2, ATXN10, ATXN2 | SIGMAR1 2505/4885HTR2A 168/4885HTR2C 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.