Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597144 | 0.82 | HSD17B10 (0.58) | ALDH1A1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL30258384 | 0.81 | RAB9A (0.64) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL4256409 | 0.81 | RAB9A (0.64) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL17747133 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL2823735 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL28491071 | 0.80 | KMT2A (0.62) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL754748 | 0.78 | KMT2A (0.59) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL28238437 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL11873963 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2APKMMAPTKDM4E | |
| SCHEMBL4452103 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2APKMMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180523-B2 | Design, synthesis and use of synthetic nucleotides comprising charge mass tags | QUANTUMDX GROUP LIMITED (GB) | 2021-11-23 | — | — | US | disclosed |
| US-10759824-B2 | Design, synthesis and use of synthetic nucleotides comprising charge mass tags | QUANTUMDX GROUP LIMITED (GB) | 2020-09-01 | — | — | US | disclosed |
| US-20190248827-A1 | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS | QUANTUMDX GROUP LIMITED (GB) | 2019-08-15 | — | — | US | disclosed |
| US-10273261-B2 | Design, synthesis and use of synthetic nucleotides comprising charge mass tags | QUANTUMDX GROUP LIMITED (GB) | 2019-04-30 | — | — | US | disclosed |
| US-20190004055-A1 | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS | QUANTUMDX GROUP LIMITED (GB) | 2019-01-03 | — | — | US | disclosed |
| WO-2017120148-A1 | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS | QUANTUMDX GROUP LIMITED (GB) | 2017-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180523-B2 | Design, synthesis and use of synthetic nucleotides comprising charge mass tags | POLM, RNGTT, TYMP | ALDH1A1 3873/4885KMT2A 1303/4885PKM 2042/4885 |
| US-20190004055-A1 | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS | POLM, RNGTT, TYMP | ALDH1A1 3873/4885KMT2A 1303/4885PKM 2042/4885 |
| US-10759824-B2 | Design, synthesis and use of synthetic nucleotides comprising charge mass tags | POLM, RNGTT, TYMP | ALDH1A1 3873/4885KMT2A 1303/4885PKM 2042/4885 |
| US-20190248827-A1 | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS | POLM, RNGTT, TYMP | ALDH1A1 3873/4885KMT2A 1303/4885PKM 2042/4885 |
| US-10273261-B2 | Design, synthesis and use of synthetic nucleotides comprising charge mass tags | POLM, RNGTT, TYMP | ALDH1A1 3873/4885KMT2A 1303/4885PKM 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.