Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339175 | 0.83 | POLB (0.38) | MAOBL3MBTL1KMT2ASYKKDR | |
| SCHEMBL31212183 | 0.79 | MAOB (0.37) | MAOBCYP1A2MEN1KMT2AMCHR1 | |
| SCHEMBL25149802 | 0.75 | DYRK1A (0.36) | MAOBL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL26359406 | 0.75 | MAOB (0.35) | MAOBCYP1A2MEN1KMT2AMCHR1 | |
| SCHEMBL24231398 | 0.75 | POLQ (0.41) | MAOBKMT2ASYKAURKADAPK3 | |
| SCHEMBL407441 | 0.74 | L3MBTL1 (0.49) | L3MBTL1CYP1A2MEN1KMT2ACDK8 | |
| SCHEMBL22717449 | 0.74 | KMT2A (0.38) | MAOBL3MBTL1CYP1A2MEN1KMT2A | |
| SCHEMBL1913154 | 0.73 | KEAP1 (0.38) | MAOBL3MBTL1CYP1A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31647268 | 0.73 | L3MBTL1 (0.47) | L3MBTL1CYP1A2MEN1KMT2AKDM4E | |
| SCHEMBL31716869 | 0.72 | GABRP (0.38) | MAOBL3MBTL1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077787-A1 | ORGANIC COMPOUNDS | OAT, GPR119, OTC | MAOB 552/4885L3MBTL1 4046/4885CYP1A2 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.