Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.40 |
| ▸ | DUT | P33316 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19137754 | 0.77 | DUT (0.36) | PKMCRBNDUTALDH1A1LMNA | |
| SCHEMBL7926412 | 0.73 | PKM (0.40) | PKMCRBNDUTALDH1A1LMNA | |
| SCHEMBL11389897 | 0.72 | CRBN (0.46) | PKMCRBNDUTALDH1A1LMNA | |
| SCHEMBL9763767 | 0.72 | CRBN (0.42) | PKMCRBNDUT | |
| SCHEMBL29138724 | 0.71 | CRBN (0.44) | PKMCRBNDUTALDH1A1LMNA | |
| SCHEMBL25430771 | 0.71 | GPR84 (0.44) | CRBN | |
| SCHEMBL5916345 | 0.70 | ENPP1 (0.37) | DUT | |
| SCHEMBL20194521 | 0.69 | CRBN (0.46) | PKMCRBNDUTALDH1A1LMNA | |
| SCHEMBL3541014 | 0.69 | CRBN (0.54) | PKMCRBNDUTALDH1A1LMNA | |
| SCHEMBL3752207 | 0.68 | CRBN (0.40) | PKMCRBNDUTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044968-B1 | 6-Amino-2-oxo-pyrimidin-4-one derivatives, their preparation and their use as stabilisers for halogen-containing polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2007-04-18 | — | — | EP | disclosed |
| US-6232375-B1 | POLYVINYL CHLORIDE | WITCO VINYL ADDITIVES GMBH (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-1044968-A1 | 6-Amino-2-(thi)oxo-pyrimidin-4-one and 7-amino- 2,3-dihydrooxazolo[2,3-b]pyrimidin-5-one derivatives, their preparation and their use as stabilisers for halogen-containing polymers | Witco Vinyl Additives GmbH (DE) | 2000-10-18 | — | — | EP | disclosed |