Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.51 |
| ▸ | HINT1 | P49773 | 2/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.48 |
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 4/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22352197 | 0.93 | NT5E (0.58) | NT5EPOLBTGM2FUT5HINT1 | |
| SCHEMBL2922052 | 0.91 | POLB (0.61) | NT5EPOLBTGM2FUT5HINT1 | |
| SCHEMBL20442307 | 0.91 | POLB (0.61) | NT5EPOLBTGM2FUT5HINT1 | |
| Deoxy Adenosinediphosphate SCHEMBL5827743 | 0.87 | TGM2 (0.63) | NT5EPOLBTGM2FUT5P2RY2 | |
| SCHEMBL22352187 | 0.87 | TGM2 (0.59) | NT5EPOLBTGM2FUT5HINT1 | |
| Deoxy Adenosinediphosphate SCHEMBL5827749 | 0.87 | TGM2 (0.63) | NT5EPOLBTGM2FUT5P2RY2 | |
| SCHEMBL1913809 | 0.86 | TGM2 (0.62) | NT5EPOLBTGM2FUT5P2RY2 | |
| SCHEMBL7065119 | 0.86 | TGM2 (0.62) | NT5EPOLBTGM2FUT5P2RY2 | |
| SCHEMBL25712474 | 0.86 | TGM2 (0.62) | NT5EPOLBTGM2FUT5P2RY2 | |
| SCHEMBL646778 | 0.86 | HINT1 (0.54) | NT5EPOLBTGM2FUT5HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123669-A1 | CYCLIC DINUCLEOTIDES FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY SUCH AS CANCER | GLICK GARY (US) | 2017-07-20 | — | — | WO | disclosed |