Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395971 | 0.70 | THRB (0.56) | MEN1KMT2AADORA2BADORA3THRB | |
| SCHEMBL15331064 | 0.70 | MAPT (0.43) | MEN1KMT2ATP53DAOALDH1A1 | |
| SCHEMBL10656238 | 0.68 | ALDH1A1 (0.52) | MEN1KMT2AADORA2BALDH1A1LMNA | |
| SCHEMBL19147853 | 0.67 | ALDH1A1 (0.53) | MEN1KMT2AADORA2BALDH1A1LMNA | |
| SCHEMBL9618001 | 0.67 | KMT2A (0.50) | MEN1KMT2ATP53ADORA3MAPT | |
| SCHEMBL16474464 | 0.65 | DRD2 (0.44) | MEN1KMT2ADAOALDH1A1MAPT | |
| SCHEMBL9802893 | 0.64 | KMT2A (0.41) | MEN1KMT2AADORA2BALDH1A1LMNA | |
| SCHEMBL11502128 | 0.64 | KMT2A (0.38) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28562224 | 0.64 | KMT2A (0.60) | MEN1KMT2AADORA2BADORA3DAO | |
| SCHEMBL17457918 | 0.64 | PSMB1 (0.55) | MEN1KMT2APOLBDAOHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123823-A1 | ALKYL-, ACYL-, UREA-, AND AZA-URACIL SULFIDE:QUINONE OXIDOREDUCTASE INHIBITORS | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-07-20 | — | — | WO | disclosed |