Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844945 | 0.87 | ACKR3 (0.53) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL21844944 | 0.87 | HTR1A (0.54) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL21844836 | 0.86 | ACKR3 (0.51) | KMT2AMEN1ACKR3KCNH2HTR1A | |
| SCHEMBL21844837 | 0.84 | HTR2A (0.47) | ALDH1A1RAB9AACKR3HTR1AHTR1D | |
| SCHEMBL21844835 | 0.83 | ROCK2 (0.54) | ACKR3KCNH2HTR1AHTR1DHTR1B | |
| SCHEMBL20083898 | 0.81 | KDR (0.44) | KMT2AMEN1ACKR3KCNH2HTR1A | |
| SCHEMBL1696311 | 0.78 | MEN1 (0.70) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL19157150 | 0.77 | PARP1 (0.51) | MAPTRAB9AKMT2AMEN1KCNH2 | |
| SCHEMBL28004871 | 0.77 | ACKR3 (0.51) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL20083972 | 0.76 | NPC1 (0.52) | KDM4EMAPTRAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |