Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083972 | 0.89 | NPC1 (0.52) | ACKR3POLBNPC1RAB9AKCNK3 | |
| SCHEMBL21844944 | 0.87 | HTR1A (0.54) | ACKR3ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL21844943 | 0.87 | ALDH1A1 (0.54) | ACKR3ALDH1A1POLBRAB9AKCNK3 | |
| SCHEMBL21844837 | 0.84 | HTR2A (0.47) | ACKR3ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21844836 | 0.84 | ACKR3 (0.51) | ACKR3MEN1KMT2A | |
| SCHEMBL20083898 | 0.83 | KDR (0.44) | ACKR3MEN1KMT2A | |
| SCHEMBL21844835 | 0.83 | ROCK2 (0.54) | ACKR3 | |
| SCHEMBL20083983 | 0.81 | NPC1 (0.50) | ACKR3ALDH1A1POLBNPC1RAB9A | |
| SCHEMBL19157150 | 0.77 | PARP1 (0.51) | POLBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20083956 | 0.77 | MCHR1 (0.53) | MAPTUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |