Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844945 | 0.89 | ACKR3 (0.53) | NPC1RAB9AKMT2AKCNK3KCNK9 | |
| SCHEMBL19156951 | 0.87 | NPC1 (0.52) | NPC1RAB9AKMT2AKCNK3KCNK9 | |
| SCHEMBL19157150 | 0.85 | PARP1 (0.51) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL19157226 | 0.82 | HTR1A (0.41) | NPC1RAB9AKMT2AMEN1ACKR3 | |
| SCHEMBL21844913 | 0.78 | MCHR1 (0.48) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL21844832 | 0.77 | ACKR3 (0.50) | NPC1RAB9AKMT2AKCNK3MEN1 | |
| SCHEMBL15276830 | 0.76 | LMNA (0.61) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL21844944 | 0.76 | HTR1A (0.54) | NPC1RAB9AKMT2AKCNK3MEN1 | |
| SCHEMBL21844943 | 0.76 | ALDH1A1 (0.54) | RAB9AKMT2AKCNK3KCNK9MEN1 | |
| SCHEMBL3675463 | 0.75 | KCNK3 (0.84) | NPC1RAB9AKMT2AKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |