SCHEMBL19174176

SCHEMBL19174176

O=C(Nc1ccc2[nH]c(-c3ccccc3)nc2c1)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.74
MMP9 P14780 5/20 0.74
MMP8 P22894 5/20 0.74
MMP13 P45452 5/20 0.74
COMT P21964 2/20 0.73
HPSE Q9Y251 1/20 0.68
RAB9A P51151 5/20 0.67
NPC1 O15118 4/20 0.67
MAPT P10636 4/20 0.67
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
KDM4E B2RXH2 2/20 0.67
POLB P06746 2/20 0.67
THRB P10828 1/20 0.67
RECQL P46063 1/20 0.67
ATM Q13315 1/20 0.67
NR2E3 Q9Y5X4 1/20 0.62
CHEK2 O96017 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
TP53 P04637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19149751 0.99 MMP2 (0.73) MMP2MMP9MMP8MMP13COMT
SCHEMBL8767467 0.96 MMP2 (0.81) MMP2MMP9MMP8MMP13COMT
SCHEMBL8769518 0.95 HPSE (0.73) MMP2MMP9MMP8MMP13COMT
SCHEMBL8768340 0.94 MMP2 (0.77) MMP2MMP9MMP8MMP13COMT
SCHEMBL8768688 0.93 MMP2 (0.65) MMP2MMP9MMP8MMP13COMT
SCHEMBL8767573 0.92 MAPT (0.67) MMP2MMP9MMP8MMP13COMT
SCHEMBL6128131 0.92 HPSE (0.65) MMP2MMP9MMP8MMP13COMT
SCHEMBL14381718 0.91 MMP2 (0.69) MMP2MMP9MMP8MMP13COMT
SCHEMBL8768362 0.90 MMP2 (0.66) MMP2MMP9MMP8MMP13COMT
SCHEMBL6125964 0.90 MMP2 (0.67) MMP2MMP9MMP8MMP13COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339494-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIV PARIS CITE (FR) 2025-11-06 US disclosed
EP-4511022-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS Université Paris Cité (FR) 2025-02-26 EP disclosed
US-20240131007-A1 METHODS AND COMPOSITIONS FOR PICORNAVIRUS ANTI-VIRAL AGENTS UNIVERSITY OF CONNECTICUT 2024-04-25 US disclosed
WO-2023203162-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIVERSITE PARIS CITE (FR) 2023-10-26 WO disclosed
WO-2023203161-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIVERSITE PARIS CITE (FR) 2023-10-26 WO disclosed
EP-4265247-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS Université Paris Cité (FR) 2023-10-25 EP disclosed
EP-4265246-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS Université Paris Cité (FR) 2023-10-25 EP disclosed
US-10399966-B2 Compounds for treatment of trypanosomes and neurological pathogens and uses thereof UNIVERSITY OF WASHINGTON (US) 2019-09-03 US disclosed
US-20190031649-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2019-01-31 US disclosed
WO-2017127627-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2017-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031649-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF TSPO, GBA1, NLN MMP2 1438/4885MMP9 1226/4885MMP8 701/4885
US-10399966-B2 Compounds for treatment of trypanosomes and neurological pathogens and uses thereof TSPO, GBA1, NLN MMP2 1438/4885MMP9 1226/4885MMP8 701/4885
US-20250339494-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS IL2, CXCL10, IFNG MMP2 1373/4885MMP9 1696/4885MMP8 289/4885
US-20240131007-A1 METHODS AND COMPOSITIONS FOR PICORNAVIRUS ANTI-VIRAL AGENTS RNASEH1, HNRNPA2B1, HNRNPA1 MMP2 1444/4885MMP9 2701/4885MMP8 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.