SCHEMBL248141

SCHEMBL248141

CC(C)Cc1ccccc1OC(=O)Oc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MME P08473 1/20 0.41
ACE P12821 1/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
PPARA Q07869 1/20 0.40
ELANE P08246 1/20 0.40
MTNR1A P48039 4/20 0.39
MTNR1B P49286 4/20 0.39
HTT P42858 1/20 0.38
KCNA5 P22460 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416762 0.92 GABRA1 (0.47) POLBHPGDKDM4EHSD17B10GABRA1
SCHEMBL19181573 0.92 GABRA1 (0.47) POLBHPGDKDM4EHSD17B10GABRA1
SCHEMBL31105833 0.83 L3MBTL1 (0.43) HPGDKDM4EHSD17B10ELANE
SCHEMBL28396369 0.83 GABRA1 (0.46) POLBHPGDKDM4EHSD17B10MME
SCHEMBL1230108 0.83 L3MBTL1 (0.43) HPGDKDM4EHSD17B10ELANE
SCHEMBL247213 0.80 THRA (0.46) POLBHPGDKDM4EHSD17B10PPARA
SCHEMBL159832 0.80 PTGS2 (0.49) HPGDKDM4EHSD17B10GABRA1GABRB2
SCHEMBL6273089 0.80 ITGA4 (0.41) HPGDKDM4EHSD17B10GABRA1GABRB2
SCHEMBL1156947 0.79 CTSS (0.43) HPGDKDM4EHSD17B10GABRA1GABRB2
SCHEMBL8078601 0.79 KMT2A (0.53) HSD17B10GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3227374-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-01 EP disclosed
EP-3452530-B1 COPOLYCARBONATE AS SUPPORT MATERIAL FOR 3D PRINTING COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2020-09-30 EP disclosed
EP-3227387-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED PROCESSABILITY CONTAINING PE WAXES COVESTRO DEUTSCHLAND AG (DE) 2020-03-11 EP disclosed
US-10323145-B2 Copolycarbonate compositions with cyclic and linear oligomers and improved optical properties COVESTRO DEUTSCHLAND AG (DE) 2019-06-18 US disclosed
US-20190143582-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING COVESTRO DEUTSCHLAND AG (DE) 2019-05-16 US disclosed
EP-2496636-B1 MORE FLAME-RETARDANT POLYCARBONATE COMPOSITION FOR USE IN EXTRUDED PRODUCTS COVESTRO DEUTSCHLAND AG (DE) 2019-05-15 EP disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
US-20180179378-A1 Copolycarbonate Compositions with Cyclic and Linear Oligomers and Improved Optical Properties COVESTRO DEUTSCHLAND AG (DE) 2018-06-28 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
EP-1277781-A2 Process for preparing copolycarbonates Bayer Aktiengesellschaft (DE) 2003-01-22 EP disclosed
EP-1270638-A2 Process and use of polyestercarbonates Bayer Aktiengesellschaft (DE) 2003-01-02 EP disclosed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP disclosed
US-20020188091-A1 Process for continuous production of polycarbonates and a reactor therefor COVESTRO DEUTSCHLAND AG (DE) 2002-12-12 US disclosed
WO-2002085967-A1 METHOD FOR CONTINUOUSLY PRODUCING POLYCARBONATES ACCORDING TO THE MELT TRANSESTERIFICATION METHOD BAYER AKTIENGESELLSCHAFT (DE) 2002-10-31 WO disclosed
EP-1253163-A1 Process for continuously preparing polycarbonates by transesterification BAYER AG (DE) 2002-10-30 EP disclosed
WO-2002077067-A2 METHOD FOR PRODUCING POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077066-A1 METHOD FOR PRODUCING OLIGOCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed