Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.60 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.60 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755450 | 0.85 | ALDH1A1 (0.52) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL315471 | 0.83 | ALDH1A1 (0.55) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL10948430 | 0.83 | PLOD2 (0.83) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL2587127 | 0.82 | ALDH1A1 (0.53) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL5176902 | 0.82 | PLOD2 (0.53) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL1062957 | 0.81 | PLOD2 (0.56) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL27908332 | 0.79 | PLOD2 (0.55) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL275775 | 0.79 | KMT2A (0.67) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL3108729 | 0.79 | PLOD2 (0.64) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 | |
| SCHEMBL22129609 | 0.78 | PLOD2 (0.53) | PLOD2PLOD3PLOD1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115537406-B | Ketoreductase and application thereof in preparation of (S) -1- (4-pyridyl) -1, 3-propanediol | 尚科生物医药（上海）有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-115537406-A | Ketoreductase and application thereof in preparation of (S) -1- (4-pyridyl) -1,3-propylene glycol | 尚科生物医药（上海）有限公司 | 2022-12-30 | — | — | CN | claimed |
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | claimed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| EP-1405917-A2 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | Bayer Chemicals AG (DE) | 2004-04-07 | — | — | EP | claimed |
| EP-3820879-B1 | PHOSPHORUS-CONTAINING PRODRUGS OF GEMCITABINE | CHANGCHUN CHANGCHENG PHARMACEUTICAL TECH CO LTD (CN) | 2024-11-06 | — | — | EP | disclosed |
| CN-115537406-B | Ketoreductase and application thereof in preparation of (S) -1- (4-pyridyl) -1, 3-propanediol | 尚科生物医药（上海）有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-115537406-B | Ketoreductase and application thereof in preparation of (S) -1- (4-pyridyl) -1, 3-propanediol | 尚科生物医药（上海）有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-115537406-A | Ketoreductase and application thereof in preparation of (S) -1- (4-pyridyl) -1,3-propylene glycol | 尚科生物医药（上海）有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115537406-A | Ketoreductase and application thereof in preparation of (S) -1- (4-pyridyl) -1,3-propylene glycol | 尚科生物医药（上海）有限公司 | 2022-12-30 | — | — | CN | disclosed |
| US-20220104493-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-07 | — | — | US | disclosed |
| CN-111655710-B | Gemcitabine phosphorus-containing prodrugs | 上海长乘医药科技有限公司 | 2021-12-21 | — | — | CN | disclosed |
| WO-1996006095-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-02-29 | — | — | WO | disclosed |
| US-5401849-A | FOR ANTAGONIZING THE ACTIONS OF, AND INHIBITING THE SYNTHESIS OF, THROMBOXANE A2 | ZENECA LIMITED (GB) | 1995-03-28 | — | — | US | disclosed |
| EP-0329360-B1 | Pyridine derivatives | ICI PLC (GB) | 1994-08-03 | — | — | EP | disclosed |
| US-5248780-A | Thromboxane inhibitors | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1993-09-28 | — | — | US | disclosed |
| US-5166213-A | Antiischemic agents, cardiovascular disorders, antiasthmatics or antiinflammatory agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0329360-A2 | Pyridine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-23 | — | — | EP | disclosed |
| US-4829076-A | CARDIOVASCULAR DISORDERS | ALKALOIDA VEGYESZETI GYAR (HU) | 1989-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220104493-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | PLOD2 1321/4885PLOD3 3362/4885PLOD1 758/4885 |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | PLOD2 260/4885PLOD3 702/4885PLOD1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.