Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468603 | 0.87 | L3MBTL1 (0.38) | BUB1C5AR1 | |
| SCHEMBL19201023 | 0.80 | C5AR1 (0.32) | C5AR1 | |
| SCHEMBL19200585 | 0.76 | L3MBTL1 (0.39) | BUB1C5AR1 | |
| SCHEMBL596325 | 0.65 | ADORA1 (0.38) | C5AR1 | |
| SCHEMBL19195046 | 0.65 | NR1H2 (0.38) | BUB1C5AR1 | |
| SCHEMBL6375680 | 0.65 | C5AR1 (0.35) | C5AR1 | |
| SCHEMBL3457767 | 0.65 | F12 (0.33) | C5AR1 | |
| SCHEMBL16622327 | 0.65 | C5AR1 (0.37) | C5AR1 | |
| SCHEMBL6377226 | 0.62 | C5AR1 (0.36) | C5AR1 | |
| SCHEMBL3327257 | 0.61 | C5AR1 (0.33) | C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217991-A1 | NOVEL 3-AMINO-PYRROLO[3,4-C]PYRAZOLE-5(1H, 4H,6H) CARBALDEHYDE DERIVATIVES | PFIZER INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217991-A1 | NOVEL 3-AMINO-PYRROLO[3,4-C]PYRAZOLE-5(1H, 4H,6H) CARBALDEHYDE DERIVATIVES | INSR, IAPP, GPR119 | BUB1 1141/4885C5AR1 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.