Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MIF | P14174 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196066 | 0.89 | MAPT (0.53) | MAPTKMT2AALDH1A1MEN1HSD11B1 | |
| SCHEMBL17037974 | 0.75 | HSD11B1 (0.47) | MAPTKMT2AALDH1A1MEN1HSD11B1 | |
| SCHEMBL19196345 | 0.74 | ALDH1A1 (0.46) | MAPTKMT2AALDH1A1MEN1HSD11B1 | |
| SCHEMBL5288407 | 0.73 | ALDH1A1 (0.60) | MAPTKMT2AALDH1A1MEN1HSD11B1 | |
| SCHEMBL24803036 | 0.72 | SLC16A3 (0.43) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL17903507 | 0.72 | MEN1 (0.62) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL30361083 | 0.72 | MEN1 (0.62) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL28409979 | 0.72 | MEN1 (0.62) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL17525295 | 0.71 | MEN1 (0.61) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL19506951 | 0.71 | MEN1 (0.60) | MAPTKMT2AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10921327-B2 | Probes for quantitative imaging of thiols in various environments | BAYLOR COLLEGE OF MEDICINE (US) | 2021-02-16 | — | — | US | disclosed |
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10921327-B2 | Probes for quantitative imaging of thiols in various environments | SQOR, TXN2, TXNRD1 | MAPT 1297/4885KMT2A 3943/4885ALDH1A1 533/4885 |
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | SQOR, TXN2, TXNRD1 | MAPT 1297/4885KMT2A 3943/4885ALDH1A1 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.