Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525291 | 0.82 | MAOB (0.63) | ALDH1A1GAALMNAMAPTHPGD | |
| SCHEMBL19196312 | 0.79 | MAPT (0.49) | ALDH1A1GAACRHBPCRHR2LMNA | |
| SCHEMBL19203494 | 0.74 | MAPT (0.43) | ALDH1A1GAALMNAMAPTHSD11B1 | |
| SCHEMBL12611517 | 0.74 | ALDH1A1 (0.72) | ALDH1A1LMNAHSD11B1MIFHPGD | |
| SCHEMBL17037974 | 0.74 | HSD11B1 (0.47) | ALDH1A1GAAMAPTHSD11B1MIF | |
| SCHEMBL5288407 | 0.72 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTADORA3HSD11B1 | |
| SCHEMBL19196066 | 0.71 | MAPT (0.53) | ALDH1A1GAALMNAMAPTHSD11B1 | |
| SCHEMBL19196064 | 0.71 | MIF (0.45) | ALDH1A1GAALMNAMAPTMIF | |
| SCHEMBL19196313 | 0.69 | MAPT (0.58) | ALDH1A1LMNAMAPTRAB9AKDM4E | |
| SCHEMBL30629234 | 0.69 | NPC1 (0.70) | ALDH1A1MAPTMIFHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | SQOR, TXN2, TXNRD1 | ALDH1A1 533/4885GAA 1701/4885CRHBP 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.