SCHEMBL1920380

SCHEMBL1920380

COCCC(N)CS(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.35
TP53 P04637 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920281 0.83 SLC22A6 (0.33) LTA4HSLC22A6
SCHEMBL15381953 0.74 TP53 (0.33) TP53
SCHEMBL4830064 0.74 PIK3CD (0.35)
SCHEMBL13656056 0.73 THRB (0.42) LTA4H
SCHEMBL7639998 0.73 LMNA (0.42) LTA4HTP53SLC22A6
SCHEMBL584136 0.73 LMNA (0.42) LTA4HTP53SLC22A6
SCHEMBL1010259 0.73 SLC22A6 (0.36) LTA4HTP53SLC22A6
SCHEMBL8076303 0.72 TP53 (0.50) TP53
SCHEMBL8076301 0.72 TP53 (0.50) TP53
SCHEMBL28370787 0.71 LTA4H (0.35) LTA4HTP53SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170267632-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS INC (US) 2017-09-21 US disclosed
US-20170267632-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS INC (US) 2017-09-21 US disclosed
US-20170267632-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS INC (US) 2017-09-21 US disclosed
US-9695119-B2 Methionine analogs and methods of using same BIOXINESS PHARMACEUTICALS, INC. (US) 2017-07-04 US disclosed
US-9695119-B2 Methionine analogs and methods of using same BIOXINESS PHARMACEUTICALS, INC. (US) 2017-07-04 US disclosed
US-20170029369-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2017-02-02 US disclosed
US-20170029369-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2017-02-02 US disclosed
US-20150329481-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2015-11-19 US disclosed
US-20150329481-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2015-11-19 US disclosed
US-20150329481-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2015-11-19 US disclosed
US-20140142189-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2014-05-22 US disclosed
US-20140142189-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2014-05-22 US disclosed
US-20140142189-A1 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICALS, INC. (US) 2014-05-22 US disclosed
US-8580859-B2 Methionine analogs and methods of using same BIOXINESS PHARMACEUTICALS, INC. (US) 2013-11-12 US disclosed
EP-2326619-A2 METHIONINE ANALOGS AND METHODS OF USING SAME Bioxiness Pharmaceuticals, Inc. (US) 2011-06-01 EP disclosed
WO-2010014943-A2 METHIONINE ANALOGS AND METHODS OF USING SAME BIOXINESS PHARMACEUTICS, INC. (US) 2010-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267632-A1 METHIONINE ANALOGS AND METHODS OF USING SAME MTR, METAP1, AMD1 LTA4H 2320/4885TP53 2757/4885SLC22A6 4665/4885
US-20150329481-A1 METHIONINE ANALOGS AND METHODS OF USING SAME MTR, METAP1, AMD1 LTA4H 2320/4885TP53 2757/4885SLC22A6 4665/4885
US-20170029369-A1 METHIONINE ANALOGS AND METHODS OF USING SAME MTR, METAP1, AMD1 LTA4H 2320/4885TP53 2757/4885SLC22A6 4665/4885
US-20140142189-A1 METHIONINE ANALOGS AND METHODS OF USING SAME MTR, METAP1, AMD1 LTA4H 2320/4885TP53 2757/4885SLC22A6 4665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.