Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15723602 | 0.77 | HTR2C (0.54) | CYP11B1CYP11B2MAPTBRD4HTR2C | |
| SCHEMBL8130706 | 0.72 | CYP11B1 (0.45) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL27952100 | 0.72 | ALDH1A1 (0.69) | CYP11B1CYP11B2KDM4EALDH1A1LMNA | |
| SCHEMBL20365098 | 0.70 | HTR2C (0.54) | KDM4EALDH1A1HPGDHSD17B10BRD4 | |
| SCHEMBL1537613 | 0.68 | CYP11B1 (0.41) | CYP11B1CYP11B2HTR2CHTR2ARPS6KA5 | |
| SCHEMBL13071405 | 0.68 | CYP11B1 (0.41) | CYP11B1CYP11B2KDM4EHTR2CHTR2A | |
| SCHEMBL3971362 | 0.68 | CYP11B1 (0.41) | CYP11B1CYP11B2HTR2CHTR2ARPS6KA5 | |
| SCHEMBL10247331 | 0.68 | TSHR (0.41) | CYP11B1CYP11B2LMNAHSD17B10HTR2C | |
| SCHEMBL22005065 | 0.67 | HTR6 (0.49) | BRD4PGR | |
| SCHEMBL13299517 | 0.66 | NLRP3 (0.60) | CYP11B1CYP11B2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | CYP11B1 3532/4885CYP11B2 3580/4885KDM4E 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.